Currently using TRI/3D-BON with CBCT images
but label densitometry only measures volume
If so, do I need a phantom?
(December 13, 2022, Dr. Taku Udagawa, Tokyo Dental University)

Phantoms are not required for volume-only measurements.
Bone is extracted by CT pixel value measurement, label density measurement is OK
is. If the same CT pixel value is used for extraction,
A comparison of the results is possible.


Q

002
Using TRI/3D-BON in areas where loads are applied
Please introduce the paper that measured the increase in bone mass.
(2017/6 Dr. K, Ohashi Hospital, Faculty of Medicine, Toho University)


A

001-02

Professor N, Osaka University
Using TRI / 3D-BON, showing bone mass changes,
The following three are at least clearly written.
(1) Bone mass loss due to unloading (cutting the sciatic nerve)
A paper showing

　　Jun Wang, Takuya Ishimoto and Takayoshi Nakano*: 
　　Unloading-induced degradation of the anisotropic
　　arrangement of collagen/apatite in rat femurs,
　　Carcified Tissue International (CTIN),100 (2017)  87-94.

(2)A paper showing increased bone mass under load with an artificial hip joint

　　Yoshihiro Noyama, Takayoshi Nakano*, Takuya Ishimoto,
　　Takashi Sakai and Hideki Yoshikawa:
　　Design and optimization of the oriented groove on the hip
　　implant surface to promote bone microstructure integrity,
　　Bone, 52 (2013), pp.659-667.

(3)Paper showing increased bone mass after loading with dental implants

　　Shinichiro Kuroshima*, Takayoshi Nakano, Takuya Ishimoto,
　　Muneteru Sasaki，Maaya Inoue, Munenori Yasutake, Takashi Sawase:
　　Optimally Oriented Grooves on Dental Implants Improves Bone
　　Quality around Implants under Repetitive Mechanical Loading,
　　Acta Biomaterialia, 48 (2017), pp.433-444.



A

001-03
Asahi Kasei Pharma Mr. T
There are no documents that match your search, but
・Use your company's software
・Mechanical evaluation (strength test, FEA analysis)
・Bone structure analysis
We will introduce one of our papers including three.

　　Three-Times-Weekly Administration of Teriparatide Improves
　　Vertebral and Peripheral Bone Density, 
　　Microarchitecture,and Mechanical Properties
　　Without Accelerating Bone Resorption in Ovariectomized Rats
　　Calcif Tissue Int (2015) 97:156-168



Q

003
Output the image taken with Rigaku's micro CT as a vox file,
Analysis is underway with 3D BON FCS.
When trimming in pre-analysis processing,
<> when I press trimming execute
I get an error and can't save.
Are there any countermeasures?
(Prof. K, Tokyo Medical and Dental University 2017/6)




A

003-01
RATOC
A memory error occurs when using a 32-bit PC.
It's a windows limitation.
In that case, trim only the necessary part and open it.
(1) Menu: Open with File/New 3D Trimming.
(2) A pink square frame appears on the Open Movie panel.
   Shrink this frame to limit the data range.
   Limit Z-slices.
   You can open it now.
(3) If all areas are required, check the magnification specification
   to compress and open the image.
(4) Rotate with Trimming and limit the range.
For details, please refer to the operation manual.


Q

004
1 BV/TV: ratio in bone marrow?
2 Why is BMD correlated with BV/TV?
(Professor M, University of N, May 2018)


A

004-01
RATOC
1　Yes, that's right. 

2　The BMD image calculated from the phantom value is
American Society of Bone and Mineral Research (ASBMR) Guideline Terms
Now for the TMD image (Tissue mineral density). 
TMD=BMC/BV

BMC; bone mineral content　BV; bone volume
On the other hand, the volumetric bone density corresponding to DXA is
vBMD (volumetric Bone Mineral Density). 
vBMD=BMC/TV
TV；Total Volume=marrow area
Volume including cancellous bone. 
vBMD correlates well with BV/TV. 
On the other hand, TMD is the degree of bone mineralization, so
It does not correlate with bone mass (bone volume density BV/TV). 


Q

005
Measured values ??of phantom drawn by TRI/3D-BON (BON-FCS) are scattered
(Graph points do not lie on a straight line)
(Professor N, University of T, May 2019)


A

005-01
RATOC
Phantom color coding may not be done correctly.
When enclosing the phantom with a green frame, start from the aluminum rod side.
8, 6, 3, etc. are lined up in order from the aluminum bar



Q

006
Phantom calibration curve file does not appear in BMD image generation
(Professor S from K University May 2019)


A

006-01
RATOC
It is located where you saved the calibration file.
The default location is where you opened the phantom image.
Check the same folder as the phantom image


Q

007
Can TRI measure the volume of soft tissue such as muscle?
(Professor S, University of N 2020/1)


A

007-01
RATOC
It is possible to measure the volume of soft tissue such as muscle.
Please check the following:
(1) Does the CT show the soft tissue to be measured?
(2) Adhesion with surrounding tissue
(3) Operation: We hold TRI/3D-BON operation briefings at our company about every three months (for details, please check the "Training" menu)


Q

008
Can TRI measure the volume of soft tissue such as muscle?
(Professor S, University of N 2020/1)


A

008-01
RATOC
procedure
1. Create a tissue for the measurement site and store it in the b5 channel
2. Set L to 0, lower W, set the position where the air region you want to measure becomes yellow, and store b0 = b0 AND b5 in b3 channel
3. Bone mineral content measurement > auto execution
4. Results; Tissue: measurement site volume, bone volume: air volume, BV/TV: air volume ratio

Reference: Refer to the operation manual "Cancellous bone/cortical bone/bone mineral content measurement"